The Effects of Probiotics on Gut Health

Gut health is of critical importance for overall health and well-being. In recent years, research on the positive effects of probiotics on gut health has increased. Probiotics can alleviate various digestive issues and improve overall health by balancing the gut microbiota. In this article, we will examine the effects of probiotics on gut health.

Definition and Function of Probiotics

Probiotics are live microorganisms that provide health benefits to the host when consumed in adequate amounts. They are typically composed of bacteria such as lactobacilli and bifidobacteria. Probiotics support digestive health by balancing the gut microbiota and strengthening the immune system [1] [2].

Effects of Probiotics on Gut Health

Irritable Bowel Syndrome (IBS)

Irritable bowel syndrome (IBS) is a common digestive disorder characterized by symptoms such as abdominal pain, bloating, and irregular bowel movements. Probiotics, particularly species such as Bifidobacterium infantis 35624, have been shown to be effective in alleviating IBS symptoms [1]. However, further research is needed to determine the efficacy of other probiotic strains.

Inflammatory Bowel Diseases (IBD)

Inflammatory bowel diseases (IBD) include chronic inflammatory conditions such as Crohn's disease and ulcerative colitis. Probiotics have been suggested to be beneficial in the treatment of ulcerative colitis. However, the evidence in this area is conflicting, and further research is required [3] [4].

Antibiotic-Associated Diarrhea

Antibiotic use can disrupt the gut microbiota, leading to side effects such as diarrhea. Probiotics may be effective in preventing antibiotic-associated diarrhea. High doses of probiotics have been shown to significantly reduce the incidence of diarrhea [5].

Celiac Disease

Celiac disease is an autoimmune disorder triggered by gluten consumption. Probiotics may help alleviate symptoms of celiac disease, but evidence in this area is limited [6].

Other Health Benefits of Probiotics

Probiotics not only support digestive health but also the immune system. Additionally, certain probiotic strains have been suggested to reduce the risk of developing neuropsychiatric disorders [7]. Probiotics such as Akkermansia muciniphila have been reported to have positive effects on type 2 diabetes and related metabolic disorders [8].

Conclusion

Probiotics are beneficial microorganisms that support gut health and can alleviate various digestive issues. However, the effectiveness of probiotics may vary depending on factors such as type and dosage. Therefore, it is recommended to consult a healthcare professional before using probiotics. Further research in the future will help us better understand the effects of probiotics on gut health.

Disclaimer: The information provided on this blog is for informational purposes only and is not intended as medical advice. Please consult a healthcare professional before making any changes to your diet, lifestyle, or health regimen.

References

1. Brenner, D., Moeller, M., Chey, W., & Schoenfeld, P. The Utility of Probiotics in the Treatment of Irritable Bowel Syndrome: A Systematic Review. The American Journal of Gastroenterology. 2007; 104. https://doi.org/10.1038/ajg.2009.25

2. Gorelov, A., Zakharova, I., Khavkin, A., Kafarskaya, L., Usenko, D., Belmer, S., Kornienko, E., Privorotsky, V., Krasnov, V., Kondyurina, E., Panfilova, V., Tkhakushinova, N., Plaksina, A., Rychkova, O., Pechkurov, D., Nizhevich, A., Fayzullina, R., & Yablokova, E. Resolution of the Council of Experts “Dysbiosis. Immediate and long-term consequences of microbiome disorders and options for their correction with probiotics”. Voprosy praktičeskoj pediatrii. 2022 https://doi.org/10.20953/1817-7646-2022-1-213-221

3. Hedin, C., Graczer, M., Sanderson, J., Lindsay, J., & Whelan, K. Probiotic and prebiotic use by patients with inflammatory bowel disease. Proceedings of the Nutrition Society. 2009; 68. https://doi.org/10.1017/S0029665109001773

4. Ghavami, B., Aghdaei, A., Sorrentino, D., Shahrokh, S., Farmani, M., Ashrafian, F., Dore, M., Raftar, S., Khoramjoo, S., & Zali, M. Probiotic-Induced Tolerogenic Dendritic Cells: A Novel Therapy for Inflammatory Bowel Disease?. International Journal of Molecular Sciences. 2021; 22. https://doi.org/10.3390/ijms22158274

5. Guo, Q., Goldenberg, J., Humphrey, C., Dib, E., & Johnston, B. Probiotics for the prevention of pediatric antibiotic-associated diarrhea.. The Cochrane database of systematic reviews. 2019; 4. https://doi.org/10.1002/14651858.CD004827.pub5

6. Seiler, C., Kiflen, M., Stefanolo, J., Bai, J., Bercik, P., Kelly, C., Verdú, E., Moayyedi, P., & Pinto-Sanchez, M. A108 PROBIOTICS FOR CELIAC DISEASE: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS. Gastroenterology. 2020; 3. https://doi.org/10.1093/jcag/gwz047.107

7. Pärtty, A., Kalliomäki, M., Wacklin, P., Salminen, S., & Isolauri, E. A possible link between early probiotic intervention and the risk of neuropsychiatric disorders later in childhood: a randomized trial. Pediatric Research. 2015; 77. https://doi.org/10.1038/pr.2015.51

8. Li, J., Yang, G., Zhang, Q., Liu, Z., Jiang, X., & Xin, Y. Function of Akkermansia muciniphila in type 2 diabetes and related diseases. Frontiers in Microbiology. 2023; 14. https://doi.org/10.3389/fmicb.2023.1172400